Octahedral complexes of anti-cancer Pt(IV)(cyclohexyldiamine) agents with 9-methylguanine

X-Ray Structure of the Major Adduct of the Anticancer Drug Cisplatin with DNA: <i>cis</i> -[Pt(NH ₃ ) ₂ {d(pGpG)}]

Suzanne E. Sherman, Dan Gibson, Andrew H.‐J. Wang et al. · Science · 1985 · 409 citations

Natural Sciences, Chemistry, Oncology +17

Antitumor activity of 1,2-diaminocyclohexaneplatinum complexes against Sarcoma-180 ascites form

Yoshinori Kidani, Kenji Inagaki, Masaaki Iigo et al. · Journal of Medicinal Chemistry · 1978 · 237 citations

Medicine, Oncology, Pharmacology +9

Intrastrand bis(guanine) chelation of trinucleoside diphosphate d(CpGpG) to cis-platinum: an x-ray single-crystal structure analysis

J. L. VAN DER VEER, R. A. G. de Graaff, Jeroen H. J. Den Hartog et al. · Journal of the American Chemical Society · 1987 · 132 citations

Natural Sciences, Chemistry, Crystal Structure +13

Interaction of the antitumor agents cis,cis,trans-Pt(IV)(NH3)2Cl2(OH)2 and cis,cis,trans-Pt(IV)[(CH3)2CHNH2]2Cl2(OH)2 and their reduction products with PM2 DNA

Erich E. Blatter, Jean F. Vollano, Bala Krishnan et al. · Biochemistry · 1984 · 94 citations

Medicine, Oncology, Pharmacology +8

Reaction products from platinum(IV) amine compounds and 5'-GMP are mainly bis(5'-GMP) platinum (II) amine adducts

J. L. VAN DER VEER, Anton R. Peters, J. Reedijk · Journal of Inorganic Biochemistry · 1986 · 77 citations

Natural Sciences, Chemistry, Medicinal Chemistry +8