Transcutaneous immunization with an outer membrane protein of <i>Porphyromonas gingivalis</i> without adjuvant elicits marked antibody responses

Abstract

Since 40k-OMP-specific IgG inhibited the coaggregation of P. gingivalis with Streptococcus gordonii, and the hemagglutinin activity of P. gingivalis, TCI with the 40k-OMP may be important as an adjuvant-free immunogen for the prevention of chronic periodontitis.