Statistics in Medicine · 1984 · 25 citations · 2 references
Public HealthBiostatisticsCausal InferenceExperimental DesignMedical EthicsBias ControlClinical Trial EthicsClinical TrialsRandomized Controlled TrialsSelection BiasConsent In Clinical ResearchRandomizationRandomized Clinical TrialsRandomized Controlled Trial EthicsRandomized ExperimentsSelection Bias Analysis
Employing randomization theory, this note examines the manner in which a clinical trial employing Zelen's randomized consent design yields an estimated treatment effect free of selection bias. We also examine the concept of 'treatment dilution' in this design.
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