Molecular analysis of iron overload in β2-microglobulin-deficient mice

A novel MHC class I–like gene is mutated in patients with hereditary haemochromatosis

John N. Feder, Andreas Gnirke, Zenta Tsuchihashi et al. · Nature Genetics · 1996 · 3.7K citations

Life Sciences, Genetics, Molecular Genetics +12

Cloning and characterization of a mammalian proton-coupled metal-ion transporter

Hiromi Gunshin, Bryan Mackenzie, Urs V. Berger et al. · Nature · 1997 · 3.2K citations · Full text

Engineering, Biochemistry, Molecular Biology +10

A New Mouse Liver-specific Gene, Encoding a Protein Homologous to Human Antimicrobial Peptide Hepcidin, Is Overexpressed during Iron Overload

Christelle Pigeon, Gennady P. Ilyin, Brice Courselaud et al. · Journal of Biological Chemistry · 2001 · 1.7K citations · Full text

Medicine, Biochemistry, Molecular Genetics +17

A Novel Duodenal Iron-Regulated Transporter, IREG1, Implicated in the Basolateral Transfer of Iron to the Circulation

Andrew T. McKie, P. Marciani, Andreas Rolfs et al. · Molecular Cell · 2000 · 1.4K citations · Full text

Life Sciences, Biochemistry, Physiology +12

Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 ( <i>USF2</i> ) knockout mice

Gaël Nicolas, Myriam Bennoun, Isabelle Devaux et al. · Proceedings of the National Academy of Sciences · 2001 · 1.2K citations · Full text

Medicine, Molecular Biology, Molecular Genetics +17