Pediatric Hematology and Oncology · 2000 · 32 citations · 3 references
PharmacyInfectious DiseasesMicrobiologyAntimicrobial PharmacotherapyMycologyPediatric Infectious DiseasesAntifungal AgentsAntifungal PharmacotherapyAntifungal TherapyFungal InfectionsInfective EndocarditisTreatment Of EndocarditisAcute Myeloid Leukemia TherapyAspergillosis TherapyFungal Infections In Transplant RecipientsInfectious EndocarditisInvasive Aspergillosis ManagementInvasive Aspergillosis TreatmentInvasive Fungal InfectionsRefractory Acute Myeloid Leukemia
An 11-year-old boy underwent a matched unrelated bone marrow transplant for refractory acute myeloid leukemia. He developed invasive aspergillus pneumonia and endocarditis post-transplant. The fungal endocarditis was successfully eradicated with liposomal amphotericin at the dose of 10 mg/kg/day. Surgical intervention was not required and no serious side effects of liposomal amphotericin were observed at this dose.
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