Characterization of Blood Flow in Capillaries by Numerical Simulation

Abstract

This paper presents a numerical investigation of the axisymmetric, pressure driven motion of single file erythrocyte (i.e., red blood cell) suspensions flowing in capillaries of diameter 8-11 µm. Our study success-fully recreates several important in vivo hemodynamic and hemorheological properties of microscopic blood flow, such as parachute shape of the cells, blunt velocity profile, and the Fahraeus effect, and they have been shown to have strong dependence on cell deformability, hematocrit and vessel size.