Induction of caspase-independent apoptosis in H9c2 cardiomyocytes by adriamycin treatment

Specific proteolytic cleavage of poly(ADP-ribose) polymerase: an early marker of chemotherapy-induced apoptosis.

Scott H. Kaufmann, Serge Desnoyers, Yvonne Ottaviano et al. · PubMed · 1993 · 1.9K citations

Chemoprevention Strategy, Basal Padprp Activity, Medicine +13

Doxorubicin cardiotoxicity: analysis of prevailing hypotheses

Richard D. Olson, Phillip S. Mushlin · The FASEB Journal · 1990 · 685 citations

Effect of anthracycline antibiotics on oxygen radical formation in rat heart.

James H. Doroshow · PubMed · 1983 · 629 citations

Cardiovascular Toxicity, Redox Biology, Oxidative Stress +16

Redox cycling of anthracyclines by cardiac mitochondria. II. Formation of superoxide anion, hydrogen peroxide, and hydroxyl radical.

James H. Doroshow, Kelvin J.A. Davies · Journal of Biological Chemistry · 1986 · 547 citations · Full text

Bioorganic Chemistry, Antimicrobial Chemotherapy, Chemical Biology +21

Mechanisms of p53-dependent apoptosis

Martin Schüler, Douglas R. Green · Biochemical Society Transactions · 2001 · 501 citations

Mitophagy, P53-dependent Apoptosis, Apoptosis +18