Residual Dipolar Couplings (RDCs) Analysis of Small Molecules Made Easy: Fast and Tuneable Alignment by Reversible Compression/Relaxation of Reusable PMMA Gels

Abstract

Tuneable RDCs: A fast and tunable method for measuring anisotropic NMR parameters using variable compression/relaxation of clean and reusable PMMA gels in CDCl3 is introduced (see picture). No special devices are needed. The configuration and conformation of small molecules can be determined by using the RDC slopes without the need for performing a control experiment in isotropic conditions. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.