INCREASE OF ACID PHOSPHATASE ACTIVITY IN THE MACROPHAGES BY QUARTZ PARTICLES

Abstract

The acid phosphatase activity in the macrophages rapidly increased by the addition of alkali-treated quartz particles, but did not by ground quartz particles. This rapid increase of acid phosphatase activity in the macrophages was also observed by cristobalite, but not by microcline, cyanite, tourmaline and others. β-Glucuronidase, cathepsin and alkaline phosphatase in the macrophages were not activated remarkably by the quartz particles. The activation of acid phosphatase of the cells by quartz particles was prevented by polyvinylpyridine-N-oxide.