Concepedia

Specific method for determination of OSI-774 and its metabolite OSI-420 in human plasma by using liquid chromatography–tandem mass spectrometry

Ming Zhao, Ping He, Michelle A. Rudek, Manuel Hidalgo, Sharyn D. Baker

Journal of Chromatography B · 2003 · 68 citations · 3 references

DOI

Concepts

References

3

Phase I and Pharmacologic Study of OSI-774, an Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor, in Patients With Advanced Solid Malignancies

Manuel Hidalgo, Lillian L. Siu, John Nemunaitis et al. · Journal of Clinical Oncology · 2001 · 1K citations

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BindingDB Entry 50022536: Induction of apoptosis and cell cycle arrest by CP-358,774, an inhibitor of epidermal growth factor receptor tyrosine kinase.

PubMed · 2025 · 844 citations · Full text

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Analytical methods validation: Bioavailability, bioequivalence and pharmacokinetic studies

Vinod P. Shah, K.K. Midha, S Dighe et al. · European Journal of Drug Metabolism and Pharmacokinetics · 1991 · 617 citations

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