Concepedia

exo-Selective asymmetric 1,3-dipolar cycloaddition of azomethine ylides with alkylidene malonates catalyzed by AgOAc/TF-BiphamPhos

Zhiyong Xue, Tang‐Lin Liu, Zhou Lu, He Huang, Hai‐Yan Tao, Chun‐Jiang Wang

Chemical Communications · 2010 · 77 citations · 35 references

DOI

Concepts

Abstract

The first exo-selective asymmetric 1,3-dipolar cycloaddition of alkylidene malonates with azomethine ylides catalyzed by AgOAc/TF-BiphamPhos has been reported in good yields and good to excellent enantio-/diastereoselectivities.

References

35

Readily Available Biaryl P,N Ligands for Asymmetric Catalysis

Thomas F. Knöpfel, Patrick Aschwanden, Takashi Ichikawa et al. · Angewandte Chemie International Edition · 2004 · 378 citations · Full text

, , +8

Highly Enantioselective Ag(I)-Catalyzed [3 + 2] Cycloaddition of Azomethine Ylides

James M. Longmire, Bin Wang, Xumu Zhang · Journal of the American Chemical Society · 2002 · 372 citations

, , +9

Catalytic Asymmetric [3+2] Cycloaddition of Azomethine Ylides. Development of a Versatile Stepwise, Three-Component Reaction for Diversity-Oriented Synthesis

Chuo Chen, Xiaodong Li, Stuart L. Schreiber · Journal of the American Chemical Society · 2003 · 289 citations

, , +17

A Highly Enantio‐ and Diastereoselective Cu‐Catalyzed 1,3‐Dipolar Cycloaddition of Azomethine Ylides with Nitroalkenes

Xiaoxia Yan, Qian Peng, Yan Zhang et al. · Angewandte Chemie International Edition · 2006 · 279 citations

, , +6

Asymmetric Organocatalytic Three-Component 1,3-Dipolar Cycloaddition: Control of Stereochemistry via a Chiral Brønsted Acid Activated Dipole

Xiaohua Chen, Wenquan Zhang, Liu‐Zhu Gong · Journal of the American Chemical Society · 2008 · 270 citations

, , +14