The merlin tumor suppressor interacts with Ral guanine nucleotide dissociation stimulator and inhibits its activity

Improved method for high efficiency transformation of intact yeast cells

Daniel Gietz, Andrew St. Jean, Robin A. Woods et al. · Nucleic Acids Research · 1992 · 3.3K citations · Full text

Engineering, Medicine, Biotechnology +7

Alteration in a new gene encoding a putative membrane-organizing protein causes neuro-fibromatosis type 2

Guy A. Rouleau, P. Merel, Mohini Lutchman et al. · Nature · 1993 · 1.4K citations

Neurodegenerative Diseases, Fibrosis, Developmental Biology +10

A novel moesin-, ezrin-, radixin-like gene is a candidate for the neurofibromatosis 2 tumor suppressor

James A. Trofatter · Cell · 1993 · 1.4K citations · Full text

Tumor Biology, Neuro-oncology, Radixin-like Gene +7

The NF2 tumor suppressor gene product, merlin, mediates contact inhibition of growth through interactions with CD44

Helen Morrison, Larry S. Sherman, James Legg et al. · Genes & Development · 2001 · 532 citations · Full text

Mice heterozygous for a mutation at the Nf2 tumor suppressor locus develop a range of highly metastatic tumors

Andrea I. McClatchey, Ichiko Saotome, Kristina B. Mercer et al. · Genes & Development · 1998 · 379 citations · Full text

Cancer Pathology, Metastatic Tumors, Pathology +17