Concepedia

Oxidation of a critical thiol residue of the adenine nucleotide translocator enforces Bcl-2-independent permeability transition pore opening and apoptosis

Paola Costantini, Anne-Sophie Belzacq, Helena L.A. Vieira, Nathanaël Larochette, Manuel A. de Pablo, Naoufal Zamzami, Santos A. Susín, Catherine Brenner, Guido Kroemer

Oncogene · 2000 · 280 citations · 37 references

DOI

Concepts

References

37

Induction of Apoptotic Program in Cell-Free Extracts: Requirement for dATP and Cytochrome c

Xuesong Liu, Caryn Naekyung Kim, Jie Yang et al. · Cell · 1996 · 5.2K citations · Full text

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Prevention of Apoptosis by Bcl-2: Release of Cytochrome c from Mitochondria Blocked

Jie Yang, Xuesong Liu, Kapil N. Bhalla et al. · Science · 1997 · 4.9K citations

, , +17

The Release of Cytochrome c from Mitochondria: A Primary Site for Bcl-2 Regulation of Apoptosis

Ruth M. Kluck, Ella Bossy‐Wetzel, Douglas R. Green et al. · Science · 1997 · 4.7K citations

, , +17

Molecular characterization of mitochondrial apoptosis-inducing factor

Santos A. Susín, Hans Kristian Lorenzo, Naoufal Zamzami et al. · Nature · 1999 · 4K citations

, , +14

Bcl-2 functions in an antioxidant pathway to prevent apoptosis

David M. Hockenbery, Zoltán N. Oltvai, Xiao-Ming Yin et al. · Cell · 1993 · 3.4K citations

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