Concepedia

High levels of synovial fluid osteoprotegerin (OPG) and increased serum ratio of receptor activator of nuclear factor-κB ligand (RANKL) to OPG correlate with disease severity in patients with primary knee osteoarthritis

Anastasia Pilichou, Ioannis Papassotiriou, Kelly Michalakakou, Smaragdi Fessatou, Emmanuel Fandridis, G. Papachristou, Evangelos Terpos

Clinical Biochemistry · 2008 · 62 citations · 10 references

DOI

Concepts

References

10

Osteoprotegerin: A Novel Secreted Protein Involved in the Regulation of Bone Density

W. Scott Simonet, Dave Lacey, Colin R. Dunstan et al. · Cell · 1997 · 5.1K citations · Full text

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Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand

Hailing Hsu, David L. Lacey, Colin R. Dunstan et al. · Proceedings of the National Academy of Sciences · 1999 · 1.6K citations

, , +17

Soluble receptor activator of nuclear factor κB ligand–osteoprotegerin ratio predicts survival in multiple myeloma: proposal for a novel prognostic index

Evangelos Terpos, Richard Szydlo, Jane F. Apperley et al. · Blood · 2003 · 413 citations · Full text

, , +15

Osteoprotegerin expression in synovial tissue from patients with rheumatoid arthritis, spondyloarthropathies and osteoarthritis and normal controls

David R. Haynes · British journal of rheumatology · 2002 · 159 citations

, , +17

Human rheumatoid synovial fibroblasts promote osteoclastogenic activity by activating RANKL via TLR-2 and TLR-4 activation

Kyoung‐Woon Kim, Mi‐La Cho, Sang‐Heon Lee et al. · Immunology Letters · 2007 · 149 citations

, , +16