Silver(<scp>i</scp>)-mediated highly enantioselective synthesis of axially chiral allenes under thermal and microwave-assisted conditions

Abstract

Silver(I) salts mediated stereospecific transformation of optically active propargylamines to axially chiral allenes with excellent enantioselectivities (17 examples with 96-99% ee; one substrate with 91% ee) without subsequent racemization.