Age-related Risk Factors, Culture Outcomes, and Prognosis in Patients Admitted With Infectious Keratitis to Two Dutch Tertiary Referral Centers

Abstract

Infectious keratitis is a more severe disease in elderly than in younger patients with more complications and a worse prognosis. Elderly patients have multiple and more diverse risk factors, making prevention difficult. Prevention should aim at minimizing topical steroid use and controlling blepharitis, ocular surface disease, and herpetic eye disease. Initial antibiotic treatment should include sufficient coverage of Gram-positive pathogens.