Importance of hydropathic complementarity for the binding of the neuropeptide substance P to a monoclonal antibody: Equilibrium and kinetic studies

A simple method for displaying the hydropathic character of a protein

Jack Kyte, Russell F. Doolittle · Journal of Molecular Biology · 1982 · 23.1K citations

Life Sciences, Biochemistry, Molecular Biology +12

Protein Design by Binary Patterning of Polar and Nonpolar Amino Acids

Satwik Kamtekar, Jarad Schiffer, Huayu Xiong et al. · Science · 1993 · 744 citations

Life Sciences, Biochemistry, Bioengineering +17

Experimental design for kinetic analysis of protein-protein interactions with surface plasmon resonance biosensors

Robert Karlsson, Anders Fält · Journal of Immunological Methods · 1997 · 565 citations

Life Sciences, Biochemistry, Biophysics +17

Determination of Rate and Equilibrium Binding Constants for Macromolecular Interactions Using Surface Plasmon Resonance: Use of Nonlinear Least Squares Analysis Methods

Daniel J. O’Shannessy, Michael Brigham‐Burke, K. Karl Soneson et al. · Analytical Biochemistry · 1993 · 551 citations

Natural Sciences, Biophysics, Chemistry +14

Bound water molecules and conformational stabilization help mediate an antigen-antibody association.

Thirumaleshwara N. Bhat, G.A. Bentley, G. Boulot et al. · Proceedings of the National Academy of Sciences · 1994 · 480 citations

Life Sciences, Biochemistry, Biophysics +17