The American Journal of Sports Medicine · 1983 · 367 citations · 53 references
MedicineOrthopaedic SurgeryOrthopedic SurgeryReconstructive SurgeryShoulder SurgeryWound HealingLigament DisordersLigament InjuriesLigament ReconstructionScar FormationSurgical Wound HealingWound ClosureHealing Tissue FormationLigament Healing After InjuryLigament Healing MechanicsMedial Collateral Ligament BiomechanicsRabbit ModelsScar Formation MechanicsScar HealingTissue Healing Response
Medial collateral ligament healing without treatment has been studied in a rabbit model. Complete midsubstance gaps were found to heal by distinct scar formation over time. This healing process was fast since the gap was bridged quickly; however, more subtle changes in appearance of the healing tissue continued for many months. The ligament "scar" was found to be structurally abnormal chemically and mechanically even at long-term followup. A plateau in its improvement suggests that the scar may never approach normal ligament characteristics (without treatment). A baseline of ligament healing by scar formation has been established.
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METHOD FOR THE DETERMINATION OF HEXOSAMINES IN TISSUES
Norman F. Boas · Journal of Biological Chemistry · 1953 · 1.5K citations · Full text