Intravital microscopy reveals endothelial dysfunction in resistance arterioles in Angiotensin II-induced hypertension

Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone.

Sanjay Rajagopalan, Stephan Kurz, Thomas Münzel et al. · Journal of Clinical Investigation · 1996 · 2.4K citations · Full text

Life Sciences, Pharmacology, Physiology +16

Dorsal skinfold chamber technique for intravital microscopy in nude mice.

Hans‐Anton Lehr, Michael Leunig, Michael D. Menger et al. · PubMed · 1993 · 310 citations

Medicine, Anatomy, Bioengineering +6

Down-regulation of the expression of endothelial NO synthase is likely to contribute to glucocorticoid-mediated hypertension

Thomas Wallerath, Klaus K. Witte, Stephan Schäfer et al. · Proceedings of the National Academy of Sciences · 1999 · 288 citations

Medicine, Pharmacology, Physiology +13

Vascular Superoxide Production and Vasomotor Function in Hypertension Induced by Deoxycorticosterone Acetate–Salt

Mark J. Somers, Kreton Mavromatis, Zorina S. Galis et al. · Circulation · 2000 · 279 citations

Life Sciences, Cardiology, Physiology +15

Role of NAD(P)H oxidase on vascular alterations in angiotensin II-infused mice

Agostino Virdis, Mário Fritsch Neves, Farhad Amiri et al. · Journal of Hypertension · 2004 · 243 citations

Medicine, Cardiology, Pharmacology +17