Bisphosphonates modulate vital functions of human osteoblasts and affect their interactions with breast cancer cells

CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis

Bin‐Zhi Qian, Jiufeng Li, Hui Zhang et al. · Nature · 2011 · 2.9K citations · Full text

Medicine, Cancer Biology, Oncology +14

Nitrogen-Containing Bisphosphonates Inhibit the Mevalonate Pathway and Prevent Post-Translational Prenylation of GTP-Binding Proteins, Including Ras

Steven P. Luckman, D. E. Hughes, Fraser P. Coxon et al. · Journal of Bone and Mineral Research · 1998 · 1.2K citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Pamidronate prevents skeletal complications and is effective palliative treatment in women with breast carcinoma and osteolytic bone metastases

Allan Lipton, Richard L. Theriault, Gabriel N. Hortobagyi et al. · Cancer · 2000 · 673 citations

Medicine, Oncology, Pharmacotherapy +17

Determination of cell number in monolayer cultures

Robert J. Gillies, Nicolás Didier, Michael L. Denton · Analytical Biochemistry · 1986 · 649 citations

Life Sciences, Cell Biology, Cell Division +7

Bisphosphonates inhibit breast and prostate carcinoma cell invasion, an early event in the formation of bone metastases.

S. Boissier, Mercedes Ferreras, Olivier Peyruchaud et al. · PubMed · 2000 · 573 citations

Medicine, Oncology, Pharmacology +17