Concepedia

Pregabalin is a potent and selective ligand for α2δ-1 and α2δ-2 calcium channel subunits

Zheng Li, Charles P. Taylor, Mark L. Weber, Julie Piechan, Faith Prior, Feng Bian, Mei Cui, Diane C. Hoffman, Sean D. Donevan

European Journal of Pharmacology · 2011 · 150 citations · 26 references

DOI

Concepts

References

26

Analysis of radioligand binding experiments

Grant A. McPherson · Journal of Pharmacological Methods · 1985 · 1.2K citations

, , +9

Pregabalin for the treatment of postherpetic neuralgia

Robert H. Dworkin, A. Corbin, James P. Young et al. · Neurology · 2003 · 762 citations

, , +13

Identification of the α <sub>2</sub> -δ-1 subunit of voltage-dependent calcium channels as a molecular target for pain mediating the analgesic actions of pregabalin

Mark J. Field, Peter J. Cox, Emma Stott et al. · Proceedings of the National Academy of Sciences · 2006 · 590 citations

, , +15

The Increased Trafficking of the Calcium Channel Subunit α <sub>2</sub> δ-1 to Presynaptic Terminals in Neuropathic Pain Is Inhibited by the α <sub>2</sub> δ Ligand Pregabalin

Claudia S. Bauer, Manuela Nieto‐Rostro, Wahida Rahman et al. · Journal of Neuroscience · 2009 · 421 citations · Full text

, , +17

A Randomized, Double-Blind, Placebo-Controlled, Fixed-Dose, Multicenter Study of Pregabalin in Patients With Generalized Anxiety Disorder

Douglas E. Feltner, Jerri G. Crockatt, Steven J. Dubovsky et al. · Journal of Clinical Psychopharmacology · 2003 · 261 citations

, , +17