A simple linker for the attachment of aldehydes to the solid phase. Application to solid phase synthesis by the multipin™ method

N-methoxy-n-methylamides as effective acylating agents

Steven Nahm, Steven M. Weinreb · Tetrahedron Letters · 1981 · 1.8K citations

Pharmacy, Medicinal Chemistry, Pharmacology +5

Combinatorial Synthesis of Small Organic Molecules

Friedhelm Balkenhohl, Christoph von dem Bussche‐Hünnefeld, Annegret Lansky et al. · Angewandte Chemie International Edition in English · 1996 · 724 citations

Pharmacy, Chemistry, Medicinal Chemistry +14

An Efficient Synthesis of Optically Active α-(<i>t</i>-Butoxycarbonylamino)-aldehydes from α-Amino Acids

Jean‐Alain Fehrentz, Bertrand Castro · Synthesis · 1983 · 349 citations

Natural Sciences, Biochemistry, Chemistry +9

Pseudo-Prolines as a Solubilizing, Structure-Disrupting Protection Technique in Peptide Synthesis

Torsten Wöhr, Franck Olivier Wahl, Adel Nefzi et al. · Journal of the American Chemical Society · 1996 · 341 citations · Full text

Life Sciences, Biochemistry, Protein Folding +14

Preparation and application of the 5-(4-(9-fluorenylmethyloxycarbonyl)aminomethyl-3,5-dimethoxyphenoxy)-valeric acid (PAL) handle for the solid-phase synthesis of C-terminal peptide amides under mild conditions

Fernando Alberício, Nancy Kneib‐Cordonier, Sara Biancalana et al. · The Journal of Organic Chemistry · 1990 · 327 citations

Natural Sciences, Biochemistry, Chemistry +14