Evidence that inhibition of insulin receptor signaling activity by PC-1/ENPP1 is dependent on its enzyme activity

Mutations in ENPP1 are associated with 'idiopathic' infantile arterial calcification

Frank Rutsch, Nico Ruf, Sucheta M. Vaingankar et al. · Nature Genetics · 2003 · 603 citations

Life Sciences, Genetics, Molecular Genetics +8

Variants of ENPP1 are associated with childhood and adult obesity and increase the risk of glucose intolerance and type 2 diabetes

Nabila Bouatia‐Naji, Agnès Tounian, Chantal Samson et al. · Nature Genetics · 2005 · 321 citations · Full text

Medicine, Endocrinology, Endocrine Genetics +13

Membrane glycoprotein PC-1 and insulin resistance in non-insulin-dependent diabetes mellitus

Betty A. Maddux, Paolo Sbraccia, Shinobu Kumakura et al. · Nature · 1995 · 313 citations

Medicine, Biochemistry, Endocrinology +10

PC-1 Nucleoside Triphosphate Pyrophosphohydrolase Deficiency in Idiopathic Infantile Arterial Calcification

Frank Rutsch, Sucheta M. Vaingankar, Kristen Johnson et al. · American Journal Of Pathology · 2001 · 300 citations · Full text

Medicine, Biochemistry, Pediatrics +6

A polymorphism (K121Q) of the human glycoprotein PC-1 gene coding region is strongly associated with insulin resistance.

Antonio Pizzuti, Lucia Frittitta, A. Argiolas et al. · Diabetes · 1999 · 239 citations

Medicine, Genetics, Molecular Genetics +11