Preincisional dextromethorphan decreases postoperative pain and opioid requirement after modified radical mastectomy

The Symbol receptor antagonist dextromethorphan selectively reduces temporal summation of second pain in man

Donald D. Price, Jianren Mao, Hanan Frenk et al. · Pain · 1994 · 368 citations

Medicine, Neuroscience, Pharmacology +17

High‐dose oral dextromethorphan versus placebo in painful diabetic neuropathy and postherpetic neuralgia

Kristine A. Nelson, Karen M. Park, Elaine Robinovitz et al. · Neurology · 1997 · 358 citations

Medicine, Pharmacology, Pharmacotherapy +17

Differential effects of excitatory amino acid antagonists on dorsal horn nociceptive neurones in the rat

Anthony H. Dickenson, Ann F. Sullivan · Brain Research · 1990 · 309 citations

Life Sciences, Neuroscience, Pharmacology +16

Intrathecal treatment with dextrorphan or ketamine potently reduces pain-related behaviors in a rat model of peripheral mononeuropathy

Jianren Mao, Donald D. Price, Ronald L. Hayes et al. · Brain Research · 1993 · 240 citations

Medicine, Neuroscience, Pharmacology +16

Dextromethorphan for the treatment of neuropathic pain: a double-blind randomised controlled crossover trial with integral n-of-1 design

Henry J McQuay, Dawn Carroll, Alejandro R. Jadad et al. · Pain · 1994 · 183 citations

Nursing, Pharmacology, Pharmacotherapy +17