Intraoperative Monitoring of Cerebral Microcirculation and Oxygenation—A Feasibility Study Using a Novel Photo-Spectrometric Laser-Doppler Flowmetry

Abstract

Increase of rvCBF by paCO2 indicates a preserved CO2 reactivity independent of propofol anesthesia. The consecutive rise in srvO2 implies enhanced oxygen availability due to vasodilatation. Unchanged rvHb represents constant venous hemoglobin concentration. As expected, calculated avDO2 decreases with increased paCO2, whereas aCMRO2 remains unchanged. Despite the promising technical approach, the technology needs validation and further investigation for usage during neurosurgery.