Organic Letters · 2001 · 30 citations · 18 references
Natural SciencesChemistryCatalysisOrganic ChemistryDiversity-oriented SynthesisHeterocycle SynthesisHeterocyclic ChemistryOrganic SynthesisTemplate-directed SynthesisCross-coupling CatalysisDiversity-generating ReactionsHeterocycle FunctionalizationKetone FunctionalizationKetonesPalladium-catalyzed Cross-couplingReaction Template Design
[reaction: see text]. Two consecutive palladium-catalyzed coupling reactions from a readily available difluoroenol stannane set the stage for the synthesis of a range of difluoro- and halodifluoromethyl ketones upon a variable aryl template.
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