Concepedia

Genetic susceptibility to asthma and atopy among Chinese in Singapore – linkage to markers on chromosome 5q31–33

Lynette Pei‐Chi Shek, A.H.N. Tay, Fook Tim Chew, Denise Goh, B. W. Lee

Allergy · 2001 · 45 citations · 18 references

DOI

Abstract

This study has shown linkage of atopy and asthma to chromosome 5q31-33 in a heterogeneous Chinese population. These findings further substantiate the notion that chromosome 5q31-33 contains "universally" important susceptibility genes for these traits.

References

18

Parametric and nonparametric linkage analysis: a unified multipoint approach.

Leonid Kruglyak, Mark J. Daly, Mary Pat Reeve-Daly et al. · PubMed · 1996 · 2.9K citations · Full text

Linkage Analysis of <i>IL4</i> and Other Chromosome 5q31.1 Markers and Total Serum Immunoglobulin E Concentrations

David G. Marsh, John D. Neely, Daniel R. Breazeale et al. · Science · 1994 · 1K citations

A Polymorphism* in the 5 ′ Flanking Region of the CD14 Gene Is Associated with Circulating Soluble CD14 Levels and with Total Serum Immunoglobulin E

Mauro Baldini, I. Carla Lohman, Marilyn Halonen et al. · American Journal of Respiratory Cell and Molecular Biology · 1999 · 847 citations

A genome-wide search for quantitative trait loci underlying asthma

Scott E. Daniels, S.S. Bhattacharrya, N. I. Leaves et al. · Nature · 1996 · 786 citations

, , +6

A genome-wide search for asthma susceptibility loci in ethnically diverse populations

Nature Genetics · 1997 · 713 citations

, , +11