Concepedia

CD4+ T-Cell???Dependent Immune Damage of Liver Parenchymal Cells Is Mediated by Alloantibody

Phillip H. Horne, Keri E. Lunsford, Anna M. Eiring, Yue Wang, Donghong Gao, Ginny L. Bumgardner

Transplantation · 2005 · 23 citations · 28 references

DOI

Abstract

Collectively, these data support the hypothesis that acute immune damage of allogeneic hepatocytes by the CD4-dependent pathway is mediated by alloantibody and that this pathway is favored when Th1- or cell-mediated cytotoxic effector immune mechanisms are impaired.

References

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