OPTICAL COHERENCE TOMOGRAPHY-RASTER SCANNING AND MANUAL SEGMENTATION IN DETERMINING DRUSEN VOLUME IN AGE-RELATED MACULAR DEGENERATION

Abstract

Drusen volume as determined by spectral domain-OCT correlates with AREDS-determined drusen area and AREDS grade in nonexudative AMD. The correlation is not perfect, however, because drusen area and volume average 40% and 82% of the variation, respectively. Drusen volume can provide additional information in grading the severity of eyes with dry AMD.