Influence of Maternal Murine Immunization with <i>Dermatophagoides pteronyssinus</i> Extract on the Type I Hypersensitivity Response in Offspring

Abstract

Our study showed that maternal immunization with Dp promotes the transference of specific antibodies and/or TGF-beta, which can negatively modulate the allergic response in offspring, and suggests that maternal preexposure to allergen before mating can protect mice during the early phase.