Concepedia

Pyrimidines. XVII. I‐(Tetrahydro‐2‐pyranyl)cytosine, ‐uracil, ‐thymine and related compounds

C. Wayne Noell, C. C. Cheng

Journal of Heterocyclic Chemistry · 1966 · 13 citations · 25 references

DOI

Concepts

Abstract

Abstract In view of the reported biological activities of antibiotics Amicetin and Blasticidin S, 1‐(tetrahydro‐2‐pyranyl)cytosine, ‐uracil, ‐thymine and related compounds were synthesized. These compounds were prepared by the Hilbert‐Johnson method from 2‐chloro‐tetrahydropyran and corresponding 2,4‐dimethoxypyrimidines.

References

25

Thiation of Nucleosides. II. Synthesis of 5-Methyl-2'-deoxycytidine and Related Pyrimidine Nucleosides<sup>1</sup>

Jack J. Fox, Dina Van Praag, Iris Wempen et al. · Journal of the American Chemical Society · 1959 · 220 citations

, , +13

RESEARCHES ON PYRIMIDINES. CXV. ALKYLATION ON NITROGEN OF THE PYRIMIDINE CYCLE BY APPLICATION OF A NEW TECHNIQUE INVOLVING MOLECULAR REARRANGEMENTS

Guido E. Hilbert, Treat B. Johnson · Journal of the American Chemical Society · 1930 · 118 citations

, , +12

Purine Nucleosides. I. The Synthesis of Certain 6-Substituted-9-(tetrahydro-2-pyranyl)-purines as Models of Purine Deoxynucleosides<sup>1</sup>

Roland K. Robins, Erik F. Godefroi, Edward C. Taylor et al. · Journal of the American Chemical Society · 1961 · 103 citations

, , +11

The Chemistry of Amicetin, a New Antibiotic<sup>1,2</sup>

Edwin H. Flynn, J. W. Hinman, E. Louis Caron et al. · Journal of the American Chemical Society · 1953 · 88 citations

, , +5

Antitumor Activity and Structural Relationships of Purine Derivatives and Related Compounds against Neoplasms in Experimental Animals

Roland K. Robins · Journal of Medicinal Chemistry · 1964 · 78 citations

, , +10