Factors Associated With Decreased Kidney Function in HIV-Infected Adults Enrolled in the MTCT-Plus Initiative in Sub-Saharan Africa

Abstract

The prevalence of clinically significant kidney disease was low in this relatively healthy population of HIV-infected adults, and few participants would have required ART dose reductions. These findings support recent World Health Organization guidelines to initiate ART without routine laboratory screening. Our findings suggest that available laboratory resources could be targeted to older persons and those with very low CD4+ cell count.