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Synthesis of 2-(thienyl-2-yl or -3-yl)-4-furyl-6-aryl pyridine derivatives and evaluation of their topoisomerase I and II inhibitory activity, cytotoxicity, and structure–activity relationship

Structure–activity RelationshipPyridine DerivativesMedicinal ChemistryDerivativesNatural SciencesMedicineIi Inhibitory ActivityOrganic ChemistryChemistryPharmacologyPharmaceutical ChemistrySynthetic ChemistryDrug DiscoveryNatural Product Synthesis