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Sfpi1/PU.1 mutations in mouse radiation-induced acute myeloid leukaemias affect mRNA and protein abundance and associate with disrupted transcription

ChromatinTranscriptional RegulationSfpi1/pu.1 MutationsDisrupted TranscriptionMedicineGeneticsMixed-phenotype Acute LeukemiaRadiation EffectCell BiologyCancer GeneticsRadiation BiologyProtein AbundanceRadiation OncologyGene ExpressionTumor BiologyMyeloid Neoplasia