Concepedia

New Decalin Derivatives, Eujavanoic Acids A and B, from <i>Eupenicillium </i><i>j</i><i>avanicum</i>

Shigeru Okamoto, Tomoo Hosoe, Takeshi Itabashi, Koohei Nozawa, Kaoru Okada, Galba Maria de Campos‐Takaki, Minoru Chikamori, Takashi Yaguchi, Kazutaka Fukushima, Makoto Miyaji,

Journal of Natural Products · 2004 · 15 citations · 3 references

DOI

Concepts

Abstract

Two new decalin derivatives, eujavanoic acids A (1) and B (2), were isolated from Eupenicillium javanicum, along with several compactin derivatives. The structures of 1 and 2 were determined by spectroscopic methods and modified Mosher's method. The side chain (2-methylbutanoyloxy) and acid functionalities of compactin derivatives were necessary to show the antifungal activity.

References

3

High-field FT NMR application of Mosher's method. The absolute configurations of marine terpenoids

Ikuko I. Ohtani, Takenori Kusumi, Yoel Kashman et al. · Journal of the American Chemical Society · 1991 · 3.2K citations

, , +5

Antifungal Substances Against Pathogenic Fungi, Talaroconvolutins, from <i>Talaromyces convolutus</i>

Shohei Suzuki, Tomoo Hosoe, Koohei Nozawa et al. · Journal of Natural Products · 2000 · 83 citations · Full text

, , +11

Antifungal activity of pyranone and furanone derivatives, isolated from Aspergillus sp. IFM51759, against Aspergillus fumigatus

Shin‐ichirou Komai, Tomoo Hosoe, Koohei Nozawa et al. · JSM Mycotoxins · 2003 · 22 citations · Full text

, , +9