Acute Lymphocytic Leukemia in Owl Monkeys Inoculated with <i>Herpesvirus saimiri</i>

Abstract

Our study demonstrates for the first time that Herpesvirus saimiri can induce acute lymphocytic leukemia in owl monkeys (Aotus trivirgatus) and that malignant lymphoma can be induced in this species of nonhuman primates by the inoculation of the virus by various routes (intravenous, sub-cutaneous, and intradermal).