The effect of gastro-intestinal mucus on drug absorption

Physiology of the Gastrointestinal Tract.

Annals of Internal Medicine · 1982 · 2K citations

Life Sciences, Anatomy, Physiology +12

Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells

Per Artursson, Johan Karlsson · Biochemical and Biophysical Research Communications · 1991 · 1.9K citations

Pharmacy, Pharmacokinetics, Pharmacology +16

Physiology of the Digestive Tract.

Annals of Internal Medicine · 1961 · 582 citations

Life Sciences, Anatomy, Physiology +12

Absorptive and mucus-secreting subclones isolated from a multipotent intestinal cell line (HT-29) provide new models for cell polarity and terminal differentiation.

C. Huet, C Sahuquillo-Merino, Evelyne Coudrier et al. · The Journal of Cell Biology · 1987 · 343 citations · Full text

Life Sciences, Biochemistry, Cell Biology +15

Delineation of the Dimensions and Permeability Characteristics of the Two Major Diffusion Barriers to Passive Mucosal Uptake in the Rabbit Intestine

Henrik Westergaard, John M. Dietschy · Journal of Clinical Investigation · 1974 · 269 citations · Full text

Pharmacy, Cell Biology, Physiology +17