Does the excitatory amino acid receptor antagonist 2-APH exhibit anxiolytic activity?

Validation of open : closed arm entries in an elevated plus-maze as a measure of anxiety in the rat

Sharon Pellow, Philippe Chopin, Sandra E. File et al. · Journal of Neuroscience Methods · 1985 · 5.8K citations

Social Sciences, Behavioral Sciences, Psychology +9

Benzodiazepine receptors in rat brain

Richard F. Squires · Nature · 1977 · 1.5K citations

Medicine, Neuroscience, Pharmacology +10

Specific benzodiazepine receptors in rat brain characterized by high-affinity (3H)diazepam binding.

Richard F. Squires · Proceedings of the National Academy of Sciences · 1977 · 1.3K citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +12

Effects of alpha-adrenoceptor agonists and antagonists in a maze-exploration model of ?fear?-motivated behaviour

Sheila L. Handley, Siddika Mithani · Naunyn-Schmiedeberg s Archives of Pharmacology · 1984 · 960 citations

Medicine, Neuroscience, Pharmacology +13

Anticonvulsant Action of Excitatory Amino Acid Antagonists

M. J. Croucher, J.F. Collins, B.S. Meldrum · Science · 1982 · 693 citations

Medicine, Neuroscience, Pharmacology +16