Experimental Biology and Medicine · 1956 · 27 citations · 0 references
Life SciencesDevelopmental BiologyNutritional SciencesMaternal NutritionMaternal-fetal MedicineMicronutrient DeficiencyFetal DevelopmentFetal PhysiologyMaternal Micronutrient DeficiencyMaternal-fetal PhysiologyNutritional DeficienciesPrenatal DevelopmentFetal Reproductive DevelopmentIntrauterine Fetal DeathMaternal Vitamin MetabolismPregnancy-related Deficiency
Fetal development in the rat was severely affected by a 36-hour period of pteroylglutamic acid deficiency when instituted early in the second week of pregnancy. The incidence of fetal death or abnormality was higher when the vitamin-deficient diet was started on the 8th day of pregnancy than on the 7 th day but decreased rapidly thereafter with increasing fetal age.