Maggots and wound healing: an investigation of the effects of secretions from<i>Lucilia sericata</i>larvae upon interactions between human dermal fibroblasts and extracellular matrix components

Abstract

L. sericata larval secretions modify fibroblast adhesion and spreading across ECM protein surfaces, while keeping cells viable. Proteolytic activity of the ES played a significant role. If transferred to the wound situation, such alteration of fibroblast-ECM interactions may enhance new tissue formation.