Proceedings of the Royal Society B Biological Sciences · 2005 · 131 citations · 20 references
Veterinary MedicineInfectious Disease ControlInfectious DiseasesEmerging Infectious DiseasesEpidemiologySpatial EpidemiologyDisease EpidemiologyDisease GeographyDisease SpreadInfectious Disease DynamicsSpatial Distribution Of DiseaseVector Population DynamicsGeographical Heterogeneity In TransmissionHeterogeneityHeterogeneity In Disease SpreadIndividual-based ModelsIndividual-based Population ModelsSpatial Disease DynamicsSpatial Epidemiology ModelingSpatial Heterogeneity Of Infection
The importance of spatial heterogeneity and spatial scales (at a village or neighbourhood scale) has been explored with individual-based models. Our reasoning is based on the Chilean Easter Island (EI) case, where a first dengue epidemic occurred in 2002 among the relatively small population localized in one village. Even in this simple situation, the real epidemic is not consistent with homogeneous models. Conversely, including contact heterogeneity on different scales (intra-households, inter-house, inter-areas) allows the recovery of not only the EI epidemiological curve but also the qualitative patterns of Brazilian urban dengue epidemic in more complex situations.
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