Journal of Crohn s and Colitis · 2009 · 19 citations · 11 references
Veterinary MedicineImmunologyPharmacotherapyGastroenterologyImmunotherapyInflammationCrohn Disease PharmacotherapyGastrointestinal ImmunologyGastrointestinal InflammationHuman Immunodeficiency Virus PharmacotherapyInflammatory Bowel DiseaseMucosal InflammationCrohn Disease PathologyCrohn's ColitisInflammatory Bowel Disease PathogenesisInflammatory Bowel Disease PathologyInflammatory Bowel Disease PathophysiologyInflammatory Bowel Disease Therapy
Anti-TNF-alpha is now established as a major player in the treatment of Crohn's disease, however the use of anti-TNF-alpha therapy in patients concomitantly having HIV infection and Crohn's disease is a relatively unexplored subject. There is generally some apprehension and anxiety to use infliximab in patients with HIV. One case has been reported in literature of usage of anti-TNF-alpha in HIV positive patient with Crohn's disease who was on anti-retroviral therapy. We report for the first time the successful usage of infliximab in treating Crohn's disease in an HIV positive patient who is not on any anti-retroviral treatment.
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Efficacy and safety of infliximab monotherapy for plaque-type psoriasis: a randomised trial
Umesh Chaudhari, Pat Romano, LD Mulcahy et al. · The Lancet · 2001 · 904 citations