The Effects of Treatment With Octreotide, Diuretics, or Both on Portal Hemodynamics in Nonazotemic Cirrhotic Patients With Ascites

Abstract

In nonazotemic cirrhotic patients with ascites, the combination of diuretics and octreotide improves systemic hemodynamics and inhibits the diuretic-related component of the activated renin-aldosterone axis, which in turn augments the portal hypotensive effect of diuretic-induced plasma volume depletion.