Concepedia

6-Hydroxybuspirone Is a Major Active Metabolite of Buspirone: Assessment of Pharmacokinetics and 5-Hydroxytryptamine1A Receptor Occupancy in Rats

Harvey Wong, Randy Dockens, Lori Pajor, Suresh Yeola, James E. Grace, Arlene Stark, Rebecca Taub, Frank D. Yocca, Robert Zaczek, Yuwen Li

Drug Metabolism and Disposition · 2007 · 36 citations · 24 references

DOI

References

24

Cloning, functional expression, and mRNA tissue distribution of the rat 5-hydroxytryptamine1A receptor gene.

Paul R. Albert, Qun‐Yong Zhou, H H Van Tol et al. · Journal of Biological Chemistry · 1990 · 447 citations · Full text

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Neuronal circuits involved in the anxiolytic effects of the 5-HT1A receptor agonists 8-OH-DPAT, ipsapirone and buspirone in the rat

Rudy Schreiber, Jean De Vry · European Journal of Pharmacology · 1993 · 139 citations

, , +11

Differential Occupancy of Somatodendritic and Postsynaptic 5HT1A Receptors by Pindolol A Dose-Occupancy Study with [11C]WAY 100635 and Positron Emission Tomography in Humans

Daniel Martínez · Neuropsychopharmacology · 2001 · 124 citations

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Course and treatment of atypical depression.

Andrew A. Nierenberg, Jonathan E. Alpert, Joel A. Pava et al. · PubMed · 1998 · 118 citations

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1-(2-Pyrimidinyl)-Piperazine as Active Metabolite of Buspirone in Man and Rat

Silvio Caccia, I Conti, Gianluigi Vigan ograve et al. · Pharmacology · 1986 · 116 citations

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