Monocional Antibodies into the '90s: The All-Purpose Tool

Continuous cultures of fused cells secreting antibody of predefined specificity

Georges Köhler, César Milstein · Nature · 1975 · 17.2K citations

Pharmacy, Cell Biology, Immunology +11

Quantitative estimation of proteins by electrophoresis in agarose gel containing antibodies

Carl‐Bertil Laurell · Analytical Biochemistry · 1966 · 4.4K citations

Life Sciences, Biochemistry, Molecular Biology +12

Interferon-γ and B Cell Stimulatory Factor-1 Reciprocally Regulate Ig Isotype Production

Clifford M. Snapper, William E. Paul · Science · 1987 · 1.9K citations

Life Sciences, Cell Biology, Immunology +17

Reshaping human antibodies for therapy

Lutz Riechmann, Herman Waldmann, Greg Winter · Nature · 1988 · 1.6K citations

Pharmacy, Immunology, Pharmaceutical Biotechnology +12

Replacing the complementarity-determining regions in a human antibody with those from a mouse

Peter Jones, Paul H. Dear, Jefferson Foote et al. · Nature · 1986 · 1.4K citations

Pharmacy, Immunology, Molecular Biology +13