Journal of Heterocyclic Chemistry · 1977 · 26 citations · 3 references
Natural SciencesChemistryMedicinal ChemistryOrganic ChemistryHeterocycle SynthesisHeterocyclic ChemistryOrganic SynthesisAmino Acid DerivativesEnamine ChemistryEnamine Formation
Abstract The 5‐ and/or 6‐alkyl substituted derivatives of 2‐aminopyridine‐3‐carbonitrile were synthesized via dienamine intermediates (3) produced by the addition‐elimination reaction of various enamines to methoxymethylene malondinitrile. The reaction can be carried out without the isolation of the dienamine intermediates.
3