Copper-catalyzed C–C bond cleavage and intramolecular cyclization: an approach toward acridones

Abstract

A copper-catalyzed approach for the synthesis of acridones via C–C bond cleavage and intramolecular cyclization using air as the oxidant under neutral conditions is described. This transformation offers an alternative method to prepare medicinally important acridones and a new strategy for C–C bond cleavage.