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Amplification of the Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 lytic origin of DNA replication is dependent upon a cis-acting AT-rich region and an ORF50 response element and the trans-acting factors ORF50 (K-Rta) and K8 (K-bZIP)

Viral ReplicationOrf50 Response ElementNatural SciencesTrans-acting Factors Orf50PathogenesisPathologyMolecular BiologyVirologyHerpesvirusesDna ReplicationMedicineViral OncologyVirus GeneViral GeneticsCancer-associated Virus