Method development and validation for the chiral separation of peptides in the presence of cyclodextrins using capillary electrophoresis and experimental design

Simultaneous Optimization of Several Response Variables

George C. Derringer, Ronald C. Suich · Journal of Quality Technology · 1980 · 5.1K citations

Architecture, Materials Engineering, Design Optimization +15

Handbook of Chemometrics and Qualimetrics: Part A

Eric R. Ziegel, D. Massart, B. Vandeginote et al. · Technometrics · 1998 · 896 citations

Natural Sciences, Chemistry, Analytical Chemistry +9

Pharmaceutical Experimental Design

Eric R. Ziegel, Gareth Lewis, Didier Mathieu et al. · Technometrics · 2000 · 518 citations

Public Health, Pharmacology, Dose-response Modeling +4

Optimization of solvent strength and selectivity for reversed-phase liquid chromatography using an interactive mixture-design statistical technique

Joseph L. Glajch, J. J. Kirkland, Karen M. Squire et al. · Journal of Chromatography A · 1980 · 490 citations

Pharmacy, Chemistry, Analytical Chemistry +15

Simultaneous optimization of several chromatographic performance goals using Derringer's desirability function

Bernard Bourguignon, D.L. Massart · Journal of Chromatography A · 1991 · 107 citations

Pharmacy, Pharmaceutical Analysis, Analytical Chemistry +12