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In utero analysis of fetal growth: a sonographic weight standard.
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1991
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Obstetric ImagingUniform VarianceFetal MedicineGynecologyFetal HealthAnatomyFetal WeightFetal GrowthEmbryologyHigh-risk PregnancyBody CompositionPrenatal CarePublic HealthInfertilityMedicineMaternal HealthStandard DeviationPrenatal DiagnosisMaternal-fetal MedicineMidwiferyPediatricsPregnancyPreterm BirthIntrapartum UltrasoundUtero AnalysisWomen's Health
The study compares its fetal weight data with other prenatal ultrasound curves and large postnatal weight studies. A regression model was built from 392 mainly middle‑class white pregnancies to estimate in‑utero fetal weight. The model shows fetal weight rising from 35 g at 10 weeks to 3,619 g at 40 weeks with a constant ±12.7 % variance, achieving mean percent differences of 0.8 % and absolute percent errors of 3.3 % versus 1,771 reference fetuses and 1.1 % versus 163 delivery cases.
Regression analysis was used to develop an in utero fetal weight model from a population of 392 predominantly middle-class white patients with certain menstrual histories. There was a gradual increase in fetal weight from 35 g at 10 weeks to 3,619 g at 40 weeks, with uniform variance of +/- 12.7% (1 standard deviation) throughout gestation. When tested against the estimated weights of 1,771 chromosomally normal fetuses between 14 and 21 weeks, the mean percent difference was 0.8% and the average absolute percent error was 3.3%. When compared with actual delivery data for 163 fetuses in the group, the mean percent difference was 0.8% and the average absolute percent error was 1.1%. These data are compared with other prenatal weight curves obtained at ultrasound and with data from several large postnatal weight studies.